验证数据展示
Planning an IHC experiment? We recommend our IHCeasy MTCO2/COX2 Ready-To-Use IHC Kit. MTCO2/COX2 primary antibody included.
For other applications, we recommend the unconjugated version of this antibody, 55070-1-AP
发表文章中的应用
| WB | See 1 publications below |
产品信息
CL650-55070 targets MTCO2 in WB applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | cytochrome c oxidase II |
| 别名 | COII, COX2, COXII, cytochrome c oxidase II, Cytochrome c oxidase subunit 2, MT CO2, MTCO2 |
| 计算分子量 | 26 kDa |
| 观测分子量 | 23-26 kDa |
| GenBank蛋白编号 | YP_003024029 |
| 基因名称 | MTCO2 |
| Gene ID (NCBI) | 4513 |
| RRID | AB_2920458 |
| 偶联类型 | CoraLite® Plus 647 Fluorescent Dye |
| 最大激发/发射波长 | 654 nm / 674 nm |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA , pH 7.3 |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
COX2, also named as COII, COXII and MTCO2, belongs to the cytochrome c oxidase subunit 2 family. It is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. Defects in COX2 are a cause of mitochondrial complex IV deficiency (MT-C4D). The antibody is specific to COX2.
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CL Plus 647 MTCO2 antibody CL650-55070 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |