验证数据展示
Planning an IHC experiment? We recommend our IHCeasy MRP1/ABCC1 Ready-To-Use IHC Kit. MRP1/ABCC1 primary antibody included.
发表文章中的应用
| WB | See 1 publications below |
| IHC | See 1 publications below |
产品信息
25340-1-AP targets MRP1 in WB, IHC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IHC |
| 经测试反应性 | human |
| 文献引用反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| 别名 | ABC29, ABCC, ABCC1, MRP, MRP1 |
| 计算分子量 | 173 kDa |
| GenBank蛋白编号 | NM_004996 |
| 基因名称 | MRP1 |
| Gene ID (NCBI) | 4363 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P33527 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Multidrug resistant-associated protein 1 (MRP1, also known as ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier.
