• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • IP experiment of HepG2 using 11481-2-AP (same clone as 11481-2-PBS)

    IP experiment of HepG2 using 11481-2-AP (same clone as 11481-2-PBS)

    IP result of anti-MPG (IP:11481-2-AP, 4ug; Detection:11481-2-AP 1:300) with HepG2 cells lysate 2200 ug. This data was developed using the same antibody clone with 11481-2-PBS in a different storage buffer formulation.

  • WB analysis using 11481-2-AP (same clone as 11481-2-PBS)

    WB analysis using 11481-2-AP (same clone as 11481-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11481-2-AP (MPG antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11481-2-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 11481-2-AP (same clone as 11481-2-PBS)

    IHC staining of human prostate cancer using 11481-2-AP (same clone as 11481-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 11481-2-AP (MPG antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11481-2-PBS in a different storage buffer formulation.

MPG Polyclonal antibody, PBS Only

MPG Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 11481-2-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IP, Indirect ELISA

别名

3 alkyladenine DNA glycosylase, 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, AAG, ADPG

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

11481-2-PBS targets MPG in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag2034

Product name: Recombinant human MPG protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-293 aa of BC014991

Sequence: MPARSGAQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQPHSSSDAAQAPCPRERCLGPPTTPGPYRSIYFSSPKGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTLRKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQDEAVWLERGPLEPSEPAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQDTQA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 N-methylpurine-DNA glycosylase
别名 3 alkyladenine DNA glycosylase, 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, AAG, ADPG
计算分子量 293 aa, 32 kDa
观测分子量 33 kDa
GenBank蛋白编号BC014991
基因名称 MPG
Gene ID (NCBI) 4350
RRIDAB_2282144
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP29372
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

N-methylpurine DNA glycosylase (MPG), an initiator glycosylase of the base excision repair (BER) pathway, typically repairs alkyl-induced DNA adducts, many of which are associated with genomic instability and tumorigenic risk [PMID:22801474] MPG initiates BER by removing TMZ-induced N3-methyladenine and N7-methylguanine base lesions, leaving abasic sites (AP sites) in DNA for further processing by BER [PMID:21377995]. MPG involves in modulating the genotoxic threshold response induced by the Sn2 alkylating agent ethyl methanesulfonate (EMS) [PMID:21071726].

||
New chat Able
正在加载，请稍候...