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ML355

CAS号

1532593-30-8

分子式

C21H19N3O4S2

主要靶点

Lipoxygenase

仅限科研使用

Cat No : CM04973

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Synonyms

inhibit|12-Lipoxygenase|Lipoxygenase|LOX|ML355|ML-355|ML 355|Inhibitor

验证数据展示

  • CAS No.: 1532593-30-8

    ML355
    CAS#: 1532593-30-8

产品信息

CAS号 1532593-30-8
分子式 C21H19N3O4S2
主要靶点 Lipoxygenase
主要通路 代谢
分子量 441.52
纯度 99.26%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|12-Lipoxygenase|Lipoxygenase|LOX|ML355|ML-355|ML 355|Inhibitor

靶点活性

12-LOX:0.34 μM

溶解度

DMSO:55 mg/mL (124.57 mM)

参考文献

1.Luci DK, et al. Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. J Med Chem. 2014 Jan 23;57(2):495-506.
2.Zhang XJ, et al. An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. Nat Med. 2018 Jan;24(1):73-83.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2