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Lomitapide Mesylate

Lomitapide Mesylate (BMS-201038 mesylate) 是一种高效MTP 蛋白抑制剂，其体外IC50值为8 nM。

CAS号

202914-84-9

分子式

C40H41F6N3O5S

主要靶点

CETP

仅限科研使用

Cat No : CM05238

Print datasheet

Synonyms

AEGR-733 mesylate|甲磺酸洛美他派|BMS-201038 mesylate

验证数据展示

  • CAS No.: 202914-84-9

    Lomitapide Mesylate
    CAS#: 202914-84-9

产品信息

Lomitapide Mesylate is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.

CAS号 202914-84-9
分子式 C40H41F6N3O5S
主要靶点 CETP
主要通路 代谢
分子量 789.83
纯度 99.65%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 AEGR-733 mesylate|甲磺酸洛美他派|BMS-201038 mesylate

靶点活性

MTP:8 nM

溶解度

H2O:<1 mg/mL,Ethanol:93 mg/mL (117.7 mM),DMSO:93 mg/mL (117.7 mM)

参考文献

1.Davis KA, Miyares MA. Am J Health Syst Pharm. 2014 Jun 15;71(12):1001-8.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2