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Laninamivir

CAS号

203120-17-6

分子式

C13H22N4O7

主要靶点

Influenza Virus

仅限科研使用

Cat No : CM04756

Print datasheet

Synonyms

inhibit|Influenza Virus|influenza?neuraminidase (NA)|InfluenzaVirus|(4S,5R,6R)-5-乙酰氨基-4-胍基-6-((1R,2R)-2,3-二羟基-1-甲氧基丙基)-5,6-二氢-4H-吡喃-2-甲酸|N5|p09N1|p57N2|R 125489|R125489|R-125489|Inhibitor|Laninamivir

验证数据展示

  • CAS No.: 203120-17-6

    Laninamivir
    CAS#: 203120-17-6

产品信息

CAS号 203120-17-6
分子式 C13H22N4O7
主要靶点 Influenza Virus
主要通路 微生物学
分子量 346.34
纯度 99%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|Influenza Virus|influenza?neuraminidase (NA)|InfluenzaVirus|(4S,5R,6R)-5-乙酰氨基-4-胍基-6-((1R,2R)-2,3-二羟基-1-甲氧基丙基)-5,6-二氢-4H-吡喃-2-甲酸|N5|p09N1|p57N2|R 125489|R125489|R-125489|Inhibitor|Laninamivir

靶点活性

p57N2:3.12 nM (IC50)|N5:0.90 nM (IC50)|p09N1:1.83 nM (IC50)

体外活性

Laninamivir对p57N2、p09N1和N5展现出与Zanamivir相似的结合模式，有效抑制了包括普遍存在的His274Tyr置换在内的常见奥司他韦耐药病毒[1]。

溶解度

DMSO:Insoluble;H2O:10 mM

参考文献

1.Vavricka CJ, et al. Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog. 2011 Oct;7(10):e1002249.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2