Mibampator

Mibampator (LY451395) 是一种有效和选择性的 AMPA 受体增效剂。

CAS号

375345-95-2

分子式

C21H30N2O4S2

主要靶点

iGluR

仅限科研使用

Cat No : CM02672

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Synonyms

LY451395



产品信息

Mibampator is an effective and selective AMPA receptor potentiator.

CAS号 375345-95-2
分子式 C21H30N2O4S2
主要靶点 iGluR
主要通路 离子通道|神经科学
分子量 438.6
纯度 97.63%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 LY451395

体内活性

Mibampator reverses the central effects of an acutely intoxicating dose of ethanol in rats[1]. Mibampator dose-dependently reverses ethanol-induced deficits in both motor coordination and disruptions in an operant task in the food reward test[2].

溶解度

DMSO:20 mg/mL (45.6 mM)

参考文献

1.Zmijewski M, et al. Application of biocatalysis to drug metabolism: preparation of mammalian metabolites of a biaryl-bis-sulfonamide AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor potentiator using Actinoplanes missouriensis. Drug Metab Dispos. 2006 Jun;34(6):925-31.
2.Jones N, et al. AMPA receptor potentiation can prevent ethanol-induced intoxication. Neuropsychopharmacology. 2008 Jun;33(7):1713-23.

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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