LIN28 inhibitor LI71

CAS号

1357248-83-9

分子式

C21H21NO3

主要靶点

仅限科研使用

Cat No : CM04958

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Synonyms

inhibit|Inhibitor|MicroRNA|miRNA|LIN28|LIN28 inhibitor LI71|LIN-28 inhibitor LI71



产品信息

CAS号 1357248-83-9
分子式 C21H21NO3
主要靶点
主要通路 其他
分子量 335.4
纯度 95.88%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 inhibit|Inhibitor|MicroRNA|miRNA|LIN28|LIN28 inhibitor LI71|LIN-28 inhibitor LI71

靶点活性

LIN28:7 uM (IC50)

体外活性

LIN28 inhibitor LI71 直接结合冷冻休克域(CSD),抑制白血病细胞和胚胎干细胞中LIN28对let-7的活性。

溶解度

DMSO:27.5 mg/mL (81.99 mM)

参考文献

1.Wang L, et al. Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Cell Rep. 2018 Jun 5;23(10):3091-3101.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2