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LG-100064

CAS号

153559-46-7

分子式

C23H26O3

主要靶点

Retinoid Receptor|Autophagy

仅限科研使用

Cat No : CM06278

Print datasheet

Synonyms

Autophagy|4-[(5,6,7,8-四氢-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸|inhibit|RXRα|RXRβ|RXRγ|Retinoid Receptor|Retinoic acid receptors|RAR/RXR|Retinoid X receptors|RetinoidReceptor|Inhibitor|LG 100064|LG100064|LG-100064

验证数据展示

  • CAS No.: 153559-46-7

    LG-100064
    CAS#: 153559-46-7

产品信息

CAS号 153559-46-7
分子式 C23H26O3
主要靶点 Retinoid Receptor|Autophagy
主要通路 代谢|自噬
分子量 350.45
纯度 98.65%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Autophagy|4-[(5,6,7,8-四氢-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸|inhibit|RXRα|RXRβ|RXRγ|Retinoid Receptor|Retinoic acid receptors|RAR/RXR|Retinoid X receptors|RetinoidReceptor|Inhibitor|LG 100064|LG100064|LG-100064

靶点活性

RXRα:330 nM (EC50)|RXRγ:260 nM (EC50)|RXRβ:200 nM (EC50)

体外活性

LG-100064 shows no effect on RARα/β/γ (EC50, >10000 nM)[1].LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ.

溶解度

DMSO:49 mg/mL (139.82 mM)

参考文献

1.Marcus F. Boehm, et al. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors.

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