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GPNA hydrochloride

CAS号

67953-08-6

分子式

C11H14ClN3O5

主要靶点

Others|Apoptosis

仅限科研使用

Cat No : CM06722

Print datasheet

Synonyms

ASCT2|Apoptosis|A549|GPNA|GPNA Hydrochloride|GPNA hydrochloride|Gln|glutamine|GGT|inhibit|LAT|Inhibitor|lung|SNAT|γ-glutamyltransferase|transporter

验证数据展示

  • CAS No.: 67953-08-6

    GPNA hydrochloride
    CAS#: 67953-08-6

产品信息

CAS号 67953-08-6
分子式 C11H14ClN3O5
主要靶点 Others|Apoptosis
主要通路 凋亡
分子量 303.7
纯度 99.91%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 ASCT2|Apoptosis|A549|GPNA|GPNA Hydrochloride|GPNA hydrochloride|Gln|glutamine|GGT|inhibit|LAT|Inhibitor|lung|SNAT|γ-glutamyltransferase|transporter

体外活性

GPNA hydrochloride 是一种谷氨酰胺转运体ASCT2的抑制剂。GPNA能够可逆地诱导A549细胞发生凋亡。此外，GPNA hydrochloride 是酶γ-谷氨酰转移酶（GGT）的底物，并且还能抑制依赖Na+的载体。

溶解度

DMSO:124 mg/mL (408.3 mM)

参考文献

1.Corti A, et al. γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity. Sci Rep. 2019 Jan 29;9(1):891.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2