VEGF Receptor 2 Polyclonal antibody

VEGF Receptor 2 Polyclonal Antibody for ELISA
Cat No. 18975-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human and More (1)

应用

ELISA and More (1)

CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


发表文章中的应用

IHCSee 1 publications below

产品信息

18975-1-AP targets VEGF Receptor 2 in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 ELISA Application Description
文献引用应用IHC
经测试反应性 human
文献引用反应性mouse
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 kinase insert domain receptor (a type III receptor tyrosine kinase)
别名 CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2
计算分子量 152 kDa
GenBank蛋白编号NM_002253
基因名称 KDR
Gene ID (NCBI) 3791
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP35968
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.

发表文章

SpeciesApplicationTitle
mouseIHC

Kidney Int

TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis.

Authors - Xu Chang C
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