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JX06

CAS号

729-46-4

分子式

C10H16N2O2S4

主要靶点

Apoptosis|PDK|Dehydrogenase

仅限科研使用

Cat No : CM05827

Print datasheet

Synonyms

Apoptosis|inhibit|PDK|PDHK|PDH|PDH kinase|Pyruvate dehydrogenase kinase|Inhibitor|JX06|JX-06|JX 06

验证数据展示

  • CAS No.: 729-46-4

    JX06
    CAS#: 729-46-4

产品信息

CAS号 729-46-4
分子式 C10H16N2O2S4
主要靶点 Apoptosis|PDK|Dehydrogenase
主要通路 代谢|凋亡|PI3K/Akt/mTOR 信号通路
分子量 324.51
纯度 99.40%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Apoptosis|inhibit|PDK|PDHK|PDH|PDH kinase|Pyruvate dehydrogenase kinase|Inhibitor|JX06|JX-06|JX 06

靶点活性

PDK1:49 nM (IC50)|PDK3:313 nM (IC50)|PDK2:101 nM (IC50)

溶解度

DMSO:27.5 mg/mL (84.74 mM)

参考文献

1.Sun W , Xie Z , Liu Y , et al. JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification[J]. Cancer Research, 2015:4923-4936.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2