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Imidacloprid-urea

CAS号

120868-66-8

分子式

C9H10ClN3O

主要靶点

仅限科研使用

Cat No : CM11466

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Synonyms

Drug Metabolite|DrugMetabolite

验证数据展示

  • CAS No.: 120868-66-8

    Imidacloprid-urea
    CAS#: 120868-66-8

产品信息

CAS号 120868-66-8
分子式 C9H10ClN3O
主要靶点
主要通路 代谢
分子量 211.65
纯度 99.89%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Shipping with blue ice.
别名 Drug Metabolite|DrugMetabolite

体内活性

Imidacloprid（剂量分别为0, 5, 10, 20 mg/kg/day；口服；雌性大鼠）在大鼠的大脑、肝脏和肾脏展现出轻微的病理变化。[4]

体外活性

Imidacloprid（0、10和20μM；4-6天）能降低脂肪细胞（3T3-L1）、肝细胞（HepG2）和肌管细胞（C2C12）细胞培养模型中胰岛素刺激下的葡萄糖吸收。使用imidacloprid会抑制蛋白激酶B（AKT）和核糖体S6激酶（S6K）的磷酸化。[3]

溶解度

DMSO:112.5 mg/mL (531.5 mM );H2O:11.2 mg/mL (53.2 mM )

参考文献

1.Liu W, et al. Competitive sorption between imidacloprid and imidacloprid-urea on soil clay minerals and humic acids. J Agric Food Chem. 2002 ; 50(23):6823-6827.
2.Seifrtova M, et al. Distributions of imidacloprid, imidacloprid-olefin and imidacloprid-urea in green plant tissues and roots of rapeseed (Brassica napus) from artificially contaminated potting soil. Pest Manag Sci. 2017 ; 73(5):1010-1016.
3.Kim J, et al. Imidacloprid, a neonicotinoid insecticide, induces insulin resistance. J Toxicol Sci. 2013 ; 38(5):655-660.
4.Bhardwaj S, et al. A 90 days oral toxicity of imidacloprid in female rats: morphological, biochemical and histopathological evaluations. Food Chem Toxicol. 2010 ; 48(5):1185-1190.

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The dilution calculator equation

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