验证数据展示
产品信息
85071-1-PBS targets IL-1R2 in Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 | IL-1R2 fusion protein Eg2956 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | interleukin 1 receptor, type II |
| 别名 | CD121 antigen-like family member B, CD121b, IL-1 type II receptor, Il1r2, IL-1R-2 |
| 计算分子量 | 46 kDa |
| GenBank蛋白编号 | NM_010555.4 |
| 基因名称 | Il1r2 |
| Gene ID (NCBI) | 16178 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P27931 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane-bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 is a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.