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IWR-1

CAS号

1127442-82-3

分子式

C25H19N3O3

主要靶点

Wnt/beta-catenin

仅限科研使用

Cat No : CM06893

Print datasheet

Synonyms

endo-IWR 1|bcatenin|beta-catenin|betacatenin|Wnt/b-catenin|Wnt/betacatenin|Wnt/β-catenin|Wnt|βcatenin|IWR 1|IWR1|IWR-1|IWR-1-endo|Inhibitor|inhibit

验证数据展示

  • CAS No.: 1127442-82-3

    IWR-1
    CAS#: 1127442-82-3

产品信息

CAS号 1127442-82-3
分子式 C25H19N3O3
主要靶点 Wnt/beta-catenin
主要通路 细胞骨架|干细胞
分子量 409.44
纯度 99.82%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 endo-IWR 1|bcatenin|beta-catenin|betacatenin|Wnt/b-catenin|Wnt/betacatenin|Wnt/β-catenin|Wnt|βcatenin|IWR 1|IWR1|IWR-1|IWR-1-endo|Inhibitor|inhibit

靶点活性

Wnt:0.2 μM(EC50)

体内活性

在Wnt通路中,IWR-1 与Axin作用,发挥可逆地抑制作用。

溶解度

DMSO:15 mg/mL (36.64 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4.09 mg/mL (9.99 mM)

参考文献

1.Lu J, et al. Bioorg Med Chem Lett, 2009, 19(14), 3825-3827.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
×
×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2