IRAK2 Polyclonal antibody

IRAK2 Polyclonal Antibody for WB, ELISA
Cat No. 28200-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

Interleukin-1 receptor-associated kinase-like 2, IRAK 2, IRAK-2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse kidney tissue, mouse spleen tissue, rat kidney tissue, rat spleen tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28200-1-AP targets IRAK2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 IRAK2 fusion protein Ag28179 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin-1 receptor-associated kinase 2
别名 Interleukin-1 receptor-associated kinase-like 2, IRAK 2, IRAK-2
计算分子量 625 aa, 69 kDa
观测分子量69 kDa
GenBank蛋白编号BC125184
基因名称 IRAK2
Gene ID (NCBI) 3656
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO43187
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

IRAK2 (Interleukin-1 receptor-associated kinase 2) is a crucial protein involved in innate immune signaling and has diverse roles in various biological processes. IRAK2 belongs to the IRAK family of proteins, which share an N-terminal death domain (DD) that enables interactions with the DD-containing MyD88, and a central kinase domain (KD) (PMID: 24973222). IRAK2 has been implicated in various cancers. It is highly expressed in pancreatic cancer patients and is associated with poor prognosis. IRAK2 knockdown impairs pancreatic cancer cell proliferation (PMID: 37108068).

实验方案

Product Specific Protocols
WB protocol for IRAK2 antibody 28200-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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