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IQ-3

CAS号

312538-03-7

分子式

C20H11N3O3

主要靶点

JNK

仅限科研使用

Cat No : CM04922

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Synonyms

Inhibitor|IQ 3|IQ3|IQ-3|JNK2|JNK3|JNK1|JNK|TNF-α|inhibit|IL-6|IL-1β|IL-1α

验证数据展示

  • CAS No.: 312538-03-7

    IQ-3
    CAS#: 312538-03-7

产品信息

CAS号 312538-03-7
分子式 C20H11N3O3
主要靶点 JNK
主要通路 MAPK 信号通路
分子量 341.32
纯度 ≥98%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Inhibitor|IQ 3|IQ3|IQ-3|JNK2|JNK3|JNK1|JNK|TNF-α|inhibit|IL-6|IL-1β|IL-1α

靶点活性

JNK1:240 nM(Kd) |JNK2:290 nM(Kd)|JNK3:66 nM(Kd)

溶解度

DMSO:3.41 mg/mL (10 mM)

参考文献

1.Schepetkin I A , Kirpotina L N , Khlebnikov A I , et al. Identification and Characterization of a Novel Class of c-Jun N-terminal Kinase Inhibitors[J]. Molecular Pharmacology, 2012, 81(6):832-845.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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