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验证数据展示

  • WB analysis of HEK-293 using 11560-1-AP (same clone as 11560-1-PBS)

    WB analysis of HEK-293 using 11560-1-AP (same clone as 11560-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 11560-1-AP (ING2 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11560-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 11560-1-AP (same clone as 11560-1-PBS)

    IHC staining of human colon cancer using 11560-1-AP (same clone as 11560-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer using 11560-1-AP (ING2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11560-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with ING2 antibody included
  • IHC staining of human colon cancer using 11560-1-AP (same clone as 11560-1-PBS)

    IHC staining of human colon cancer using 11560-1-AP (same clone as 11560-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer using 11560-1-AP (ING2 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11560-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with ING2 antibody included
  • IP experiment of HEK-293 using 11560-1-AP (same clone as 11560-1-PBS)

    IP experiment of HEK-293 using 11560-1-AP (same clone as 11560-1-PBS)

    IP result of anti-ING2 (IP:11560-1-AP, 3ug; Detection:11560-1-AP 1:500) with HEK-293 cells lysate 1000ug. This data was developed using the same antibody clone with 11560-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 11560-1-AP (same clone as 11560-1-PBS)

    IF Staining of HEK-293 using 11560-1-AP (same clone as 11560-1-PBS)

    Immunofluorescent analysis of (10% Formaldehyde) fixed HEK-293 cells using 11560-1-AP (ING2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 11560-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ING2 Polyclonal antibody, PBS Only

ING2 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 11560-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy ING2 Ready-To-Use IHC Kit. ING2 primary antibody included.

产品信息

11560-1-PBS targets ING2 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag2121

Product name: Recombinant human ING2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-280 aa of BC030128

Sequence: MLGQQQQQLYSSAALLTGERSRLLTCYVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKEDDLNQKKRLQQLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSSQPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPVEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGKWYCPKCRGDNEKTMDKSTEKTKKDRRSR

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 inhibitor of growth family, member 2
别名
计算分子量 280 aa, 33 kDa
观测分子量 33 kDa
GenBank蛋白编号BC030128
基因名称 ING2
Gene ID (NCBI) 3622
RRIDAB_2127771
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9H160
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. It is induced by the DNA-damaging agent neocarzinostatin. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program. Catalog#11560-1-AP is a rabbit polyclonal antibody raised against full length ING2 of human origin.

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