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验证数据展示

  • WB analysis of human peripheral blood platelets using 12655-1-AP (same clone as 12655-1-PBS)

    WB analysis of human peripheral blood platelets using 12655-1-AP (same clone as 12655-1-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 12655-1-AP (IL-5RA antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12655-1-PBS in a different storage buffer formulation.

IL-5RA Polyclonal antibody, PBS Only

IL-5RA Polyclonal Antibody for WB, Indirect ELISA
Cat No. 12655-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

IL5RA, IL 5RA, IL 5R subunit alpha, IL 5R alpha, IL 5 receptor subunit alpha

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

12655-1-PBS targets IL-5RA in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原 IL-5RA fusion protein Ag3358 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin 5 receptor, alpha
别名 IL5RA, IL 5RA, IL 5R subunit alpha, IL 5R alpha, IL 5 receptor subunit alpha
计算分子量 48 kDa, 38 kDa
观测分子量 70-75 kDa, 43 kDa
GenBank蛋白编号BC027599
基因名称 IL-5RA
Gene ID (NCBI) 3568
RRIDAB_2127342
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ01344
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Interleukin-5 receptor subunit alpha (IL-5RA), also known as CD125, is a type I transmembrane protein that belongs to the type I cytokine receptor family. IL-5RA is a critical component of the high-affinity IL-5 receptor complex, IL-5R, which consists of the alpha chain (IL-5RA) that specifically binds to IL-5 and the common beta chain (CD131) shared with receptors for IL-3 and GM-CSF (PMID: 1833065; 7872157). IL-5/IL-5RA signaling axis is crucial for the differentiation, proliferation, recruitment, and activation of eosinophils, and is also involved in pathological eosinophilia (PMID: 34638583).