iduronate 2 sulfatase Polyclonal antibody
iduronate 2 sulfatase Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
The immunogen of 17140-1-AP is iduronate 2 sulfatase Fusion Protein expressed in E. coli.
| Tested Applications | ELISA |
| Tested Reactivity | human, mouse, rat |
| Immunogen | iduronate 2 sulfatase fusion protein Ag10904 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | iduronate 2-sulfatase |
| Synonyms | IDS, iduronate 2 sulfatase, Idursulfase |
| Calculated Molecular Weight | 312aa,35 kDa; 550aa,62 kDa |
| GenBank Accession Number | BC006170 |
| Gene Symbol | IDS |
| Gene ID (NCBI) | 3423 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P22304 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).