Recombinant Human PGLYRP1 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <1.0 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human PGLYRP1 protein Gln22-Pro196 (Accession# O75594) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 8993 |
| 蛋白编号 | O75594 |
| 预测分子量 | 45.0 kDa |
| SDS-PAGE | |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Peptidoglycan recognition protein 1 (PGLYRP1, also known as PGRP-S) belongs to a family of evolutionarily conserved innate immunity proteins, which in mammals also include PGLYRP2, PGLYRP3, and PGLYRP4. PGLYRP1 is highly expressed in polymorphonuclear leukocytes and to a lower extent in many non-immune cells. It recognizes bacterial peptidoglycan and functions in antibacterial immunity and inflammation. PGLYRP1 has been identified as a ligand for TREM-1.
参考文献:
1. Guan, Rongjin, and Roy A Mariuzza. Trends in microbiology vol. 15,3 (2007): 127-34. 2. Dziarski, Roman, and Dipika Gupta. Innate immunity vol. 16,3 (2010): 168-74. 3. Read, Christine B et al. Journal of immunology (Baltimore, Md. : 1950) vol. 194,4 (2015): 1417-21.