Recombinant Human KIR3DL1/CD158E protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <1.0 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human KIR3DL1/CD158E protein His22-His340 (Accession# P43629-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 3811 |
| 蛋白编号 | P43629-1 |
| 预测分子量 | 60.8 kDa |
| SDS-PAGE | |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. The KIR3DL1 (also named CD158E) polymorphism has been correlated with various diseases, hematopoietic stem cell transplantation (HSCT) outcomes, and viral infections.
参考文献:
1. Dupont, B et al. Tissue antigens vol. 49,6 (1997): 557-63. 2. Campbell, Kerry S, and Amanda K Purdy. Immunology vol. 132,3 (2011): 315-25. 3. Legrand, Nolwenn et al. Cancers vol. 15,10 ( 2023) 2754.