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Recombinant Human CD7 protein (rFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3034

Print datasheet

Synonyms

CD7 molecule, GP40, LEU-9, T cell antigen CD7, T cell leukemia antigen

验证数据展示

  • Purity of Recombinant Human CD7 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CD7 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human CD7 was greater than 90% as determined by SEC-HPLC.

    The purity of Human CD7 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human CD7 protein Ala26-Pro180 (Accession# P09564) with a rabbit IgG Fc tag at the C-terminus.
基因ID 924
蛋白编号 P09564
预测分子量 42.5 kDa
SDS-PAGE 47-60 kDa, reducing (R) condition
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CD7, or T-cell antigen 7 or GP40, is a transmembrane glycoprotein and a member of the immunoglobulin supergene family. CD7 is predominantly expressed on thymocytes and mature T cells, as well as natural killer (NK) cells, and it is one of the earliest antigens to appear on cells of the T-lymphocyte lineage. CD7 plays a significant role in T-cell and T-cell/B-cell interactions during early lymphoid development. It is involved in the regulation of cell signaling and biology, including T-cell activation, proliferation, and the expression of interleukin-2 receptor alpha (IL-2Rα). CD7 is not only a marker for T-cells but also has functional implications in immune cell interactions and adhesion. It can provide co-stimulatory signals and is associated with CD3 and CD45, participating in T-cell activation.

参考文献:

1. G D Sempowski. et al. (1999). Crit Rev Immunol. 19(4):331-348.
2. StillwellR. et al.(2001). Immunol Res. 24(1): 31-52.
3. WeiSD. et al. (2005). Cell Death Dis. 9(3): 293.