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Hinokitiol

Hinokitiol (4-Isopropyltropolone) 是从日本扁柏中分离到的一种挥发油成分，可抑制紫外线 B 诱导的角质形成细胞凋亡，可调节雌激素受体信号传导并抑制人乳腺癌细胞的增殖。它具有抗感染、抗氧化及抗肿瘤等活性。

CAS号

499-44-5

分子式

C10H12O2

主要靶点

Virus Protease|Estrogen/progestogen Receptor|DNA Methyltransferase|Nrf2

仅限科研使用

Cat No : CM03232

Print datasheet

Synonyms

4-Isopropyltropolone|β-thujaplicin|β-桧木醇|桧木醇

验证数据展示

  • CAS No.: 499-44-5

    Hinokitiol
    CAS#: 499-44-5

产品信息

β-thujaplicin can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent. Also, β-Thujaplicin modulates estrogen receptor signaling and inhibits proliferation of human breast cancer cells.

CAS号 499-44-5
分子式 C10H12O2
主要靶点 Virus Protease|Estrogen/progestogen Receptor|DNA Methyltransferase|Nrf2
主要通路 表观遗传|微生物学|免疫与炎症|内分泌与激素
分子量 164.2
纯度 99.49%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 4-Isopropyltropolone|β-thujaplicin|β-桧木醇|桧木醇

溶解度

Chloroform:Soluble,DMSO:29 mg/mL(176.6 mM)

参考文献

1.Ko J, et al. Biosci Biotechnol Biochem. 2015;79(6):1011-7.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2