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验证数据展示

  • WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    WB analysis of mouse brain using 13830-1-AP (same clone as 13830-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 13830-1-AP (HTR7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

  • IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    IHC staining of human brain using 13830-1-AP (same clone as 13830-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13830-1-AP (HTR7 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 13830-1-PBS in a different storage buffer formulation.

HTR7 Polyclonal antibody, PBS Only

HTR7 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 13830-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

13830-1-PBS targets HTR7 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag4742

Product name: Recombinant human HTR7 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 263-445 aa of BC047526

Sequence: YKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLQNADYCRKKGHDS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
别名
计算分子量 445 aa, 49 kDa
观测分子量 50-55 kDa
GenBank蛋白编号BC047526
基因名称 HTR7
Gene ID (NCBI) 3363
RRIDAB_2122706
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP34969
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Serotonin (5-hydroxytryptamine; 5-HT) acts as a neurotransmitter and neuromodulator in the central nervous system(CNS) (PMID:23100172). The behavioral effects of 5-HT are mediated by a large family of specific 5-HT receptors. HTR7 (5-hydroxytryptamine receptor 7) is a G protein-coupled receptor (GPCR), and many transcription factors can bind to its promoter, such as AP2, EGR-1, and MAZ (PMID:34164474). It is located in different brain regions, such as the hypothalamus, thalamus, cerebral cortex, and hippocampus (PMID:29637287). HTR7 is associated with circadian rhythm, anxiety, depression, schizophrenia, nociception, and memory (PMID:9154233).

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