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HO-3867

CAS号

1172133-28-6

分子式

C28H30F2N2O2

主要靶点

STAT|Apoptosis

仅限科研使用

Cat No : CM06554

Print datasheet

Synonyms

HO3867|HO-3867|HO 3867|inhibit|Apoptosis|Inhibitor|STAT3|STAT

验证数据展示

  • CAS No.: 1172133-28-6

    HO-3867
    CAS#: 1172133-28-6

产品信息

CAS号 1172133-28-6
分子式 C28H30F2N2O2
主要靶点 STAT|Apoptosis
主要通路 干细胞|JAK/STAT 信号通路|凋亡
分子量 464.55
纯度 99%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 HO3867|HO-3867|HO 3867|inhibit|Apoptosis|Inhibitor|STAT3|STAT

溶解度

H2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:11 mg/mL (23.68 mM);Ethanol:6 mg/mL (12.91 mM)

细胞实验

Cell viability is determined by a colorimetric assay using MTT. In the mitochondria of living cells, yellow MTT undergoes a reductive conversion to formazan, producing a purple color. Cells, grown to ~80% confluence in 75-mm flasks, are trypsinized, counted, seeded in 96-well plates with an average population of 7,000 cells/well, incubated overnight, and then treated with HO-3867 for 24 h. All experiments are done using 8 replicates and repeated at least three times. (Only for Reference)

参考文献

1.Selvendiran K, et al. Mol Cancer Ther. 2010, 9(5), 1169-1179.
2.Selvendiran K, et al. Cancer Biol Ther. 2011, 12(9), 837-845.
3.Ravi Y, et al. Hypertension. 2013, 61(3), 593-601.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2