HLA class I (HLA-B) Polyclonal antibody, PBS Only

HLA class I (HLA-B) Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Cat No. 17260-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF/ICC, IP, Indirect ELISA

HLA-B, HLA B, HLA class I histocompatibility antigen, B alpha chain, Human leukocyte antigen B, MHC class I antigen

缓冲液配方:  PBS Only
偶联物:  Unconjugated
规格价格库存


产品信息

17260-1-PBS targets HLA class I (HLA-B) in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF/ICC, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag10947

Product name: Recombinant human HLA class I (HLA-B) protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-362 aa of BC013187

Sequence: MRVTAPRTVLLLLSGALALTETWAGSHSMRYFYTAMSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWDRNTQICKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLAVVVIGAVVATVMCRRKSSGGKGGSYSQAASSDSAQGSDVSLTA

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 major histocompatibility complex, class I, B
别名 HLA-B, HLA B, HLA class I histocompatibility antigen, B alpha chain, Human leukocyte antigen B, MHC class I antigen
计算分子量 362 aa, 40 kDa
观测分子量 40-45 kDa
GenBank蛋白编号BC013187
基因名称 HLA class I (HLA-B)
Gene ID (NCBI) 3106
RRIDAB_1939610
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP01889
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44 kDa) which is encoded by a HLA class I gene (HLA-A, B or C), and β2-microglobulin light (beta) chain (12 kDa). They are involved in the presentation of foreign antigens to the immune system. This polyclonal antibody raised against human HLA-B can also react with HLA-A and HLA-C. (PMID: 667938; 3375250)

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