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验证数据展示

  • WB analysis of mouse brain using 55222-1-AP (same clone as 55222-1-PBS)

    WB analysis of mouse brain using 55222-1-AP (same clone as 55222-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 55222-1-AP (HCN1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 55222-1-AP (same clone as 55222-1-PBS)

    IHC staining of human heart using 55222-1-AP (same clone as 55222-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart using 55222-1-AP (HCN1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 55222-1-AP (same clone as 55222-1-PBS)

    IP experiment of mouse brain using 55222-1-AP (same clone as 55222-1-PBS)

    IP result of anti-HCN1 (IP:55222-1-AP, 4ug; Detection:55222-1-AP 1:1000) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 55222-1-PBS in a different storage buffer formulation.

HCN1 Polyclonal antibody, PBS Only

HCN1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 55222-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, HAC 2, Brain cyclic nucleotide-gated channel 1, BCNG-1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

55222-1-PBS targets HCN1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 hyperpolarization activated cyclic nucleotide-gated potassium channel 1
别名 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, HAC 2, Brain cyclic nucleotide-gated channel 1, BCNG-1
计算分子量 99 kDa
观测分子量 99-120 kDa
GenBank蛋白编号NM_021072
基因名称 HCN1
Gene ID (NCBI) 348980
RRIDAB_11182929
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60741
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HCN1, also named as BCNG1, belongs to the potassium channel HCN family. It hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. HCN1 contributes to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP, and at 10-100 times higher concentrations, also by cGMP. HCN1 may mediate responses to sour stimuli.

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