验证数据展示
产品信息
11746-1-PBS targets HBP1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | HBP1 fusion protein Ag2342 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | HMG-box transcription factor 1 |
别名 | |
计算分子量 | 514 aa, 58 kDa |
观测分子量 | 58 kDa |
GenBank蛋白编号 | BC022329 |
基因名称 | HBP1 |
Gene ID (NCBI) | 26959 |
RRID | AB_2247970 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O60381 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HMG-box protein 1 (HBP1) is a transcriptional repressor, and has a role in cell cycle progression and tumor suppression. Also it's a repressor of the cyclin D1 gene and inhibits the Wnt signaling pathway. Interaction with RB1 enhances it's binding to the H1F0 promoter . Disrupts the interaction between DNA and TCF4. This is a rabbit polyclonal antibody raised against part of C-terminus of HBP1 of human origin.