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验证数据展示

  • WB analysis of human brain using 11746-1-AP (same clone as 11746-1-PBS)

    WB analysis of human brain using 11746-1-AP (same clone as 11746-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 11746-1-AP (HBP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11746-1-PBS in a different storage buffer formulation.

  • WB analysis using 11746-1-AP (same clone as 11746-1-PBS)

    WB analysis using 11746-1-AP (same clone as 11746-1-PBS)

    SGC-7901 cells were subjected to SDS PAGE followed by western blot with 11746-1-AP (HBP1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11746-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse brain using 11746-1-AP (same clone as 11746-1-PBS)

    IP experiment of mouse brain using 11746-1-AP (same clone as 11746-1-PBS)

    IP result of anti-HBP1 (IP:11746-1-AP, 4ug; Detection:11746-1-AP 1:500) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 11746-1-PBS in a different storage buffer formulation.

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  • KD/KO验证

HBP1 Polyclonal antibody, PBS Only

HBP1 Polyclonal Antibody for WB, IP, Indirect ELISA
Cat No. 11746-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

11746-1-PBS targets HBP1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag2342

Product name: Recombinant human HBP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 215-514 aa of BC022329

Sequence: FLKGTRLCFHKGSNKEWQDVEDFARAEGCDNEEDLQMGIHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEVHIGDVCLPPGHPDAINFDDPGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGGQDFARSGFSKNCGSPGSSQLSSNSLYAKAVKNHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 HMG-box transcription factor 1
别名
计算分子量 514 aa, 58 kDa
观测分子量 58 kDa
GenBank蛋白编号BC022329
基因名称 HBP1
Gene ID (NCBI) 26959
RRIDAB_2247970
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60381
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HMG-box protein 1 (HBP1) is a transcriptional repressor, and has a role in cell cycle progression and tumor suppression. Also it's a repressor of the cyclin D1 gene and inhibits the Wnt signaling pathway. Interaction with RB1 enhances it's binding to the H1F0 promoter . Disrupts the interaction between DNA and TCF4. This is a rabbit polyclonal antibody raised against part of C-terminus of HBP1 of human origin.

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