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Glabridin

CAS号

59870-68-7

分子式

C20H20O4

主要靶点

Tyrosinase|PPAR|GABA Receptor|Reactive Oxygen Species|Antibacterial

仅限科研使用

Cat No : CM00282

Print datasheet

Synonyms

光甘草定|T3 tyrosinase|T1 tyrosinase|α1β2 GABAA receptor|α1β2γ2 GABAA receptor|α1β1γ2 GABAA receptor|α1β3γ2 GABAA receptor|Peroxisome proliferator-activated receptors|PPAR|ReactiveOxygenSpecies|Reactive Oxygen Species|Q 100692|Q100692|Q-100692|Inhibitor|KB 289522|KB289522|KB-289522|LS 176045|LS176045|LS-176045|Bacterial|Glabridin|GABAReceptor|GABA Receptor|inhibit

验证数据展示

  • CAS No.: 59870-68-7

    Glabridin
    CAS#: 59870-68-7

产品信息

CAS号 59870-68-7
分子式 C20H20O4
主要靶点 Tyrosinase|PPAR|GABA Receptor|Reactive Oxygen Species|Antibacterial
主要通路 NF-κB 信号通路|代谢|免疫与炎症|蛋白酶体|代谢|DNA 损伤和修复|离子通道|神经科学|微生物学
分子量 324.37
纯度 99.78%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 光甘草定|T3 tyrosinase|T1 tyrosinase|α1β2 GABAA receptor|α1β2γ2 GABAA receptor|α1β1γ2 GABAA receptor|α1β3γ2 GABAA receptor|Peroxisome proliferator-activated receptors|PPAR|ReactiveOxygenSpecies|Reactive Oxygen Species|Q 100692|Q100692|Q-100692|Inhibitor|KB 289522|KB289522|KB-289522|LS 176045|LS176045|LS-176045|Bacterial|Glabridin|GABAReceptor|GABA Receptor|inhibit

靶点活性

α1β2γ2 GABAA receptor:6.3 μM(EC50)|α1β2 GABAA receptor:9.63 μM(EC50)|α1β1γ2 GABAA receptor:17.23 μM(EC50)|α1β3γ2 GABAA receptor:6.83 μM(EC50)

溶解度

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:75 mg/mL (231.22 mM)

参考文献

1.Yokota Tm , et al. Pigment Cell Res. 1998 Dec;11(6):355-61.
2.Yehuda I, et al. Mol Nutr Food Res. 2015 Jun;59(6):1041-52.
3.Hsieh MJ, et al. Br J Pharmacol. 2014 Jun;171(12):3037-50.
4.El-Ashmawy NE, et al. Downregulation of iNOS and elevation of cAMP mediate the anti-inflammatory effect of glabridin in rats with ulcerative colitis. Inflammopharmacology. 2018 Apr;26(2):551-559.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2