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×
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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 30469-1-AP (same clone as 30469-1-PBS)

    WB analysis using 30469-1-AP (same clone as 30469-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30469-1-AP (GSDMC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

  • IHC staining of Human bowens disease using 30469-1-AP (same clone as 30469-1-PBS)

    IHC staining of Human bowens disease using 30469-1-AP (same clone as 30469-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brown disease slide using 30469-1-AP (GSDMC antibody) at dilution of 1:600 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30469-1-PBS in a different storage buffer formulation.

GSDMC Polyclonal antibody, PBS Only

GSDMC Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 30469-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

30469-1-PBS targets GSDMC in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 GSDMC fusion protein Ag33319 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gasdermin C
别名
计算分子量58kd
观测分子量58 kDa
GenBank蛋白编号NM_031415
基因名称 GSDMC
Gene ID (NCBI) 56169
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BYG8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Gasdermin (GSDM) superfamily consists of Gasdermin family genes (GSDMA, GSDMB, GSDMC and GSDMD in humans) and Gasdermin-related genes (DFNA5, DFNB59 in humans). GSDM family members were shown to be detected in the epithelium of various tissue types in a highly tissue-specific manner and suggested to have differentiation-status specific roles. Gasdermin C (GSDMC) was known as melanoma-derived leucine zipper-containing extranuclear factor (MLZE). Several studies have suggested that GSDMC may be involved in the course of tumorigenesis such as acquisition of metastatic potential in melanoma cells or promotion of cell proliferation in colorectal carcinogenesis and that GSDMC may function as an oncogene. (PMID: 29428815)