GRB10 Polyclonal antibody
GRB10 Polyclonal Antibody for WB,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB,ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | mouse brain tissue |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
10027-2-AP targets GRB10 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB,ELISA |
Tested Reactivity | human, mouse |
Immunogen | Recombinant Protein 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | growth factor receptor-bound protein 10 |
Synonyms | |
Calculated Molecular Weight | 536aa,61 kDa; 594aa,67 kDa |
Observed Molecular Weight | 65 kDa |
GenBank Accession Number | BC024285 |
Gene Symbol | GRB10 |
Gene ID (NCBI) | 2887 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q13322 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Growth factor receptor-bound protein 10 (GRB10) is an adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. GRB10 has three consensus domains including pleckstrin homology (PH) domain, SH2/SH3 domain and Ras-associating domain. By binding to kinases, GRB10 suppresses signals from activated receptors tyrosine kinases, including the INSR and INS-like growth factor (IGF1R) receptors. It may play a role in mediating INS-stimulated ubiquitination of INSR, leading to proteasomal degradation.
实验方案
Product Specific Protocols | |
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WB protocol for GRB10 antibody 10027-2-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |