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GPR37 Polyclonal antibody

GPR37 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 29989-1-AP

Print datasheet

Synonyms

EDNRBL, ETBR LP 1, GPR37, hET(B)R LP, PAELR

验证数据展示

  • WB analysis using 29989-1-AP

    WB analysis using 29989-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 29989-1-AP (GPR37 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse brain tissue, mouse cerebellum tissue, rat brain tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

29989-1-AP targets GPR37 in WB, ELISA applications and shows reactivity with Human, mouse, rat samples.

Tested Applications WB, ELISA
Tested Reactivity Human, mouse, rat
Immunogen GPR37 fusion protein Ag32431 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name G protein-coupled receptor 37 (endothelin receptor type B-like)
Synonyms EDNRBL, ETBR LP 1, GPR37, hET(B)R LP, PAELR
Calculated Molecular Weight 67 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC040007
Gene Symbol GPR37
Gene ID (NCBI) 2861
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO15354
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The orphan G protein-coupled receptor GPR37, also known as PAELR (parkin-associated endothelin receptor-like receptor) or ETBR-LP-1 (endothelin B receptor-like protein 1), is a 613 aa, multi-pass membrane protein predominantly expressed in the brain. It is a substrate of parkin (PARK2). When overexpressed in cells, GPR37 tends to become insoluble, unfolded, and ubiquitinated in vivo. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (JPD).

实验方案

Product Specific Protocols
WB protocol for GPR37 antibody 29989-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols