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验证数据展示

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

GPR137 Polyclonal antibody, PBS Only

GPR137 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 11929-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

11929-1-PBS targets GPR137 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag2611

Product name: Recombinant human GPR137 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 121-396 aa of BC033920

Sequence: VFKAKVKRRPEMSRGLLAVRGAFVGASLLFLLVNVLCAVLSHRRRAQPWALLLVRVLVSDSLFVICALSLAACLCLVARRAPSTSIYLEAKGTSVCQAAAMGGAMVLLYASRACYNLTALALAPQSRLDTFDYDWYNVSDQADLVNDLGNKGYLVFGLILFVWELLPTTLLVGFFRVHRPPQDLSTSHILNGQVFASRSYFFDRAGHCEDEGCSWEHSRGESTSMSGSLGSGSWYGAIGREPGWYGGSQTKTTPLLFSQVPGPGGHHHSLYSTPQT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 137
别名
计算分子量 396 aa, 44 kDa
GenBank蛋白编号BC033920
基因名称 GPR137
Gene ID (NCBI) 56834
RRIDAB_10694423
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96N19
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

G protein-coupled receptors (GPRs) are highly related to oncogenesis and cancer metastasis. G protein-coupled receptor 137 (GPR137) was initially reported as a novel orphan GPR about 10 years ago. GPR137 is ubiquitously expressed in the central nervous system (CNS), mainly in the hippocampus (PMID: 22025619). GPR137 is involved in the progression of human glioma, suggesting GPR137 as a potential oncogene of glioma cells (PMID: 24870220). Recent study shows that GPR137 plays an important role in colon cancer cell proliferation (PMID: 25301753).

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