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GOT1 inhibitor-1

CAS号

732973-87-4

分子式

C19H19ClN4O

主要靶点

Others

仅限科研使用

Cat No : CM06734

Print datasheet

Synonyms

ductal|inhibit|glutamate-oxaloacetate transaminase 1|GOT1|GOT1 inhibitor 1|GOT1 inhibitor 2c|GOT1 inhibitor1|GOT-1 inhibitor-1|GOT1 inhibitor-1|Cancer|adenocarcinoma|?Aspartate aminotransferase-1|metabolism|Inhibitor|Pancreatic|PDAC

验证数据展示

  • CAS No.: 732973-87-4

    GOT1 inhibitor-1
    CAS#: 732973-87-4

产品信息

CAS号 732973-87-4
分子式 C19H19ClN4O
主要靶点 Others
主要通路 其他
分子量 354.83
纯度 98.44%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 ductal|inhibit|glutamate-oxaloacetate transaminase 1|GOT1|GOT1 inhibitor 1|GOT1 inhibitor 2c|GOT1 inhibitor1|GOT-1 inhibitor-1|GOT1 inhibitor-1|Cancer|adenocarcinoma|?Aspartate aminotransferase-1|metabolism|Inhibitor|Pancreatic|PDAC

靶点活性

GOT1:8.2 μM

体外活性

在MDH耦联GOT1酶活性测定中，GOT1 inhibitor-1对GOT1活性显示出抑制作用，其IC50为8.2 μM[1]。

溶解度

DMSO:120 mg/mL (338.19 mM)

参考文献

1.Anglin J , Zavareh R B , Sander P N , et al. Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma[J]. Bioorganic & Medicinal Chemistry Letters, 2018:S0960894X18303743.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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