Fexofenadine hydrochloride

Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) 是一种抗组胺药,用于治疗过敏性鼻炎、血管性水肿和慢性荨麻疹。

CAS号

153439-40-8

分子式

C32H39NO4·HCl

主要靶点

Histamine Receptor

仅限科研使用

Cat No : CM04492

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Synonyms

MDL 16455A|盐酸非索非那定|MDL-16455 hydrochloride|Terfenidine carboxylate hydrochloride|Allegra|Telfast|Fexofenadine HCl



产品信息

Fexofenadine is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria.

CAS号 153439-40-8
分子式 C32H39NO4·HCl
主要靶点 Histamine Receptor
主要通路 神经科学|G蛋白偶联受体|免疫与炎症
分子量 538.13
纯度 99.39%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 MDL 16455A|盐酸非索非那定|MDL-16455 hydrochloride|Terfenidine carboxylate hydrochloride|Allegra|Telfast|Fexofenadine HCl

靶点活性

Histamine H1 receptor:246 nM

溶解度

DMSO:26.9 mg/mL (50 mM)

参考文献

1.Bachert C, et al. A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis. Clin Ther 31 (5): 921-44.
2.Compalati E, et al. Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials. International Archives of Allergy and Immunology 156 (1): 1-15.

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