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Feprazone

CAS号

30748-29-9

分子式

C20H20N2O2

主要靶点

Others|其他

仅限科研使用

Cat No : CM15843

Print datasheet

Synonyms

Prenazone|非普拉宗|Feprazone|DA 2370|DA2370|DA-2370

验证数据展示

  • CAS No.: 30748-29-9

    Feprazone
    CAS#: 30748-29-9

产品信息

CAS号 30748-29-9
分子式 C20H20N2O2
主要靶点 Others|其他
主要通路 其他
分子量 320.39
纯度 99.78%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 Prenazone|非普拉宗|Feprazone|DA 2370|DA2370|DA-2370

体外活性

脂质积累、三酰甘油产量增加、甘油释放、SREBP-1C、FABP4、PPAR-γ和C/EBP-α的上调以及ATGL和AQP-7的下调，在3T3-L1脂肪细胞中由脂肪细胞分化鸡尾酒培养基诱导，经Feprazone（30和60μM）[1]处理显著逆转。

溶解度

DMSO:27.5 mg/mL (85.83 mM)

参考文献

1.Berry DJ, Crome P, Corless D, Parke DV. The pharmacokinetics of single oral doses of feprazone in healthy volunteers and elderly patients. Xenobiotica. 1991 Sep;21(9):1211-6. PubMed PMID: 1788989.
2.Spahn H, Mutschler E. The influence of aluminium hydroxide on the bioavailability of feprazone. Single dose study. Arzneimittelforschung. 1985;35(1):167-9. PubMed PMID: 4039147.
3.Meloni T, Forteleoni G, Serra M, Daniotti S, Negri L, Giuntini P, Canepa L, Gaetani GF. Feprazone: absence of hemolytic effects in glucose-6-phosphate dehydrogenase-deficient subjects. J Clin Pharmacol. 1982 Aug-Sep;22(8-9):418-20. PubMed PMID: 7130431.
4.Berry D, Parke DV. The disposition of feprazone and its hydroxylated metabolite in human volunteers. Xenobiotica. 1988 Jul;18(7):857-68. PubMed PMID: 3176523.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2