验证数据展示
产品信息
87473-1-PBS targets FPR1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | formyl peptide receptor 1 |
| 别名 | fMet Leu Phe receptor, FMLP, fMLP receptor, formyl peptide receptor 1, FPR |
| 计算分子量 | 38 kDa |
| 观测分子量 | 38 kDa |
| GenBank蛋白编号 | BC005315 |
| 基因名称 | FPR1 |
| Gene ID (NCBI) | 2357 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P21462 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FPR1 is a Gi-coupled innate immune GPCR that detects formylated peptides from bacteria and damaged mitochondria, initiating leukocyte chemotaxis and inflammatory activation. Predominantly expressed in neutrophils and monocytes, FPR1 functions as a frontline danger sensor in host defense. Dysregulated FPR1 signaling contributes to infectious susceptibility, acute inflammatory injury, and tumor-associated immune modulation, underscoring its importance in innate immunity and inflammatory disease.
