验证数据展示
经过测试的应用
| Positive WB detected in | Jurkat cells, NIH/3T3 cells, HEK-293 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
23257-1-AP targets FIZ1 in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | FIZ1 fusion protein Ag19760 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | FLT3-interacting zinc finger 1 |
| 别名 | FIZ1 |
| 计算分子量 | 496 aa, 52 kDa |
| 观测分子量 | 52 kDa |
| GenBank蛋白编号 | BC136512 |
| 基因名称 | FIZ1 |
| Gene ID (NCBI) | 84922 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96SL8 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FLT3 interacting zinc finger 1 (FIZ1) is a ubiquitous expressed protein that composes of 11 C2H2 zinc finger domains spread over the entire protein in clusters of two, three, or four fingers. The interaction of FIZ1 was mapped to the catalytic domain of FLT3, which is a receptor tyrosine kinase involved in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors (10409713). In the mammalian retina, FIZ1 interacts with NRL (Neural-Retina Leucine-zipper), an essential transcriptional activator of rod photoreceptor-specific genes, and the concentration of FIZ1 in the retina will increase during photoreceptor terminal maturation (18854042).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for FIZ1 antibody 23257-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
