验证数据展示
发表文章中的应用
| WB | See 3 publications below |
| IHC | See 17 publications below |
产品信息
18705-1-AP targets F4/80 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IHC |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | human, mouse, rat |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 |
| 别名 | DD7A5 7, EGF TM7, Emr1, F4 80, F4/80, Gpf480, Ly71, TM7LN3 |
| 计算分子量 | 102 kDa |
| GenBank蛋白编号 | BC075688 |
| 基因名称 | F4/80 |
| Gene ID (NCBI) | 13733 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q61549 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Mouse F4/80, also named as EMR1 and Gpf480, is a 160kd cell surface glycoprotein which is a member of the EGF TM7 family. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. The function of F4/80 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages.
发表文章
| Species | Application | Title |
|---|---|---|
EMBO J Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma. | ||
J Am Soc Nephrol Targeted Deletion of p53 in the Proximal Tubule Prevents Ischemic Renal Injury. | ||
Aging (Albany NY) Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition. | ||
Oncotarget Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation. | ||
Clin Sci (Lond) G-CSF partially mediates bone loss induced by Staphylococcus aureus infection in mice. | ||
Sci Rep New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats. |