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Ethyl cinnamate

CAS号

103-36-6

分子式

C11H12O2

主要靶点

ROS|NO Synthase|Calcium Channel

仅限科研使用

Cat No : CM10985

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Synonyms

NO Synthase|NOSynthase|reagent|Inhibitor|ROS|肉桂酸乙酯|CalciumChannel|Calcium Channel|clearing|inhibit|Ethyl cinnamate|fragrance

验证数据展示

  • CAS No.: 103-36-6

    Ethyl cinnamate
    CAS#: 103-36-6

产品信息

CAS号 103-36-6
分子式 C11H12O2
主要靶点 ROS|NO Synthase|Calcium Channel
主要通路 免疫与炎症|免疫与炎症|离子通道|代谢
分子量 176.21
纯度 99.4%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 NO Synthase|NOSynthase|reagent|Inhibitor|ROS|肉桂酸乙酯|CalciumChannel|Calcium Channel|clearing|inhibit|Ethyl cinnamate|fragrance

靶点活性

Tonic contractions (high K+-induced):0.30 mM|Tonic contractions (chenylephrine-induced):0.38 mM

体外活性

测量了包括生物量、F(v)/F(m)（PSII最大光化合效率）、Φ(PSII)（光照条件下PSII的实际光化学效率）、FDA和PI染色荧光等参数。结果显示：(1) 随着暴露浓度的增加，对生物量的抑制作用增强。1 mg/L的Ethyl cinnamate足以减少C. vulgaris的总生物量。48小时和72小时的EC50值分别为2.07 mg/L（1.94-2.20）和1.89 mg/L（1.82-1.97）。(2) 在2-4 mg/L Ethyl cinnamate暴露24小时后，C. vulgaris的光合作用几乎停止，表现为DΦ(PSII)接近零。在4 mg/L Ethyl cinnamate暴露72小时后，C. vulgaris的Fv/Fm降至零。(3) Ethyl cinnamate也影响了C. vulgaris的细胞生理，但这些影响导致的是细胞产量的抑制而非细胞死亡[1]。

溶解度

DMSO:50 mg/mL (283.75 mM)

参考文献

1.Jiao Y, et al. Toxic Effects of Ethyl Cinnamate on the Photosynthesis and Physiological Characteristics of Chlorella vulgaris Based on Chlorophyll Fluorescence and Flow Cytometry Analysis. ScientificWorldJournal. 2015;2015:107823.
2.Anika Klingberg, et al. Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy. J Am Soc Nephrol. 2017 Feb;28(2):452-459.
3.S P Bhatia, et al. Fragrance material review on ethyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S90-4.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2