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验证数据展示

  • WB analysis using 55191-1-AP (same clone as 55191-1-PBS)

    WB analysis using 55191-1-AP (same clone as 55191-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55191-1-AP (EWS antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55191-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 55191-1-AP (same clone as 55191-1-PBS)

    IHC staining of human colon cancer using 55191-1-AP (same clone as 55191-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 55191-1-AP (EWS Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55191-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with EWSR1/EWS antibody included

EWS Polyclonal antibody, PBS Only

EWS Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 55191-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

EWSR1, EWS oncogene, RNA binding protein EWS, RNA-binding protein EWS

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy EWSR1/EWS Ready-To-Use IHC Kit. EWSR1/EWS primary antibody included.

产品信息

55191-1-PBS targets EWS in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Ewing sarcoma breakpoint region 1
别名 EWSR1, EWS oncogene, RNA binding protein EWS, RNA-binding protein EWS
计算分子量 68 kDa
观测分子量68-70 kDa
GenBank蛋白编号NM_005243
基因名称 EWS
Gene ID (NCBI) 2130
RRIDAB_10860907
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ01844
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EWS, also named as WSR1, belongs to the RRM TET family. It might normally function as a repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. This antibody is specific to EWS. And a 90 kDa band also could be detected (PMID:23552423).

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