ESR2 Beta 2 Polyclonal antibody
ESR2 Beta-2 Polyclonal Antibody for ELISA
验证数据展示
发表文章中的应用
| IF | See 1 publications below |
产品信息
55470-1-AP targets ESR2 Beta-2 in IF, ELISA applications and shows reactivity with human samples.
| Tested Applications | ELISA |
| Cited Applications | IF |
| Tested Reactivity | human |
| Cited Reactivity | human |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | estrogen receptor 2 (ER beta) |
| Synonyms | ER BETA, Erb, ESR BETA, ESRB, ESTRB, estrogen receptor 2 (ER beta), Estrogen receptor beta, NR3A2 |
| Calculated Molecular Weight | 56 kDa |
| GenBank Accession Number | NM_001437 |
| Gene Symbol | ESR2 |
| Gene ID (NCBI) | 2100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q92731 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Estrogen receptor-beta (ESR2) is a member of the superfamily of nuclear receptors, which can transduce extracellular signals into transcriptional responses. It binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual
发表文章
| Species | Application | Title |
|---|---|---|
Oncotarget Estradiol-ERβ2 signaling axis confers growth and migration of CRPC cells through TMPRSS2-ETV5 gene fusion. |