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验证数据展示

  • IHC staining of human breast cancer using 15778-1-AP (same clone as 15778-1-PBS)

    IHC staining of human breast cancer using 15778-1-AP (same clone as 15778-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 15778-1-AP (ENY2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15778-1-PBS in a different storage buffer formulation.

  • WB analysis of PC-3 using 15778-1-AP (same clone as 15778-1-PBS)

    WB analysis of PC-3 using 15778-1-AP (same clone as 15778-1-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 15778-1-AP (ENY2 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15778-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ENY2 Polyclonal antibody, PBS Only

ENY2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 15778-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

15778-1-PBS targets ENY2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 ENY2 fusion protein Ag8462 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 enhancer of yellow 2 homolog (Drosophila)
别名
计算分子量 12 kDa
观测分子量 10 kDa
GenBank蛋白编号BC007870
基因名称 ENY2
Gene ID (NCBI) 56943
RRIDAB_2878184
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NPA8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ENY2, also named as DC6, is involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. It is required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). The MW of ENY2 is about 10 kDa.