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验证数据展示

  • WB analysis of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    WB analysis of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

Dysbindin Polyclonal antibody, PBS Only

Dysbindin Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 11132-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

11132-1-PBS targets Dysbindin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Dysbindin fusion protein Ag1613 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dystrobrevin binding protein 1
别名
计算分子量 351 aa, 39 kDa
观测分子量 48 kDa, 36 kDa
GenBank蛋白编号BC011912
基因名称 Dysbindin
Gene ID (NCBI) 84062
RRIDAB_11182503
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96EV8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dysbindin, encoded by DTNBP1 (dystrobrevin binding protein 1), is a synaptic protein which is expressed in diverse neuronal populations throughout the brain. Genetic variation in DTNBP1 is associated with schizophrenia. Reduced expression of dysbindin has been reported in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia cases. Several isoforms of dysbindin exist: 48-50 kDa of dysbindin-1A, 35-38 kDa of dysbindin-1B, and 30-32 kDa of dysbindin-1C. This antibody recognizes all of isoforms of dysbindin. (19617633)