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Diphylline

Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。

CAS号

479-18-5

分子式

C10H14N4O4

主要靶点

Adenosine Receptor|PDE

仅限科研使用

Cat No : CM00045

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Synonyms

Dyphylline|二羟丙茶碱|Diprophylline

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  • CAS No.: 479-18-5

    Diphylline
    CAS#: 479-18-5

产品信息

Dyphylline is a xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosinereceptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

CAS号 479-18-5
分子式 C10H14N4O4
主要靶点 Adenosine Receptor|PDE
主要通路 代谢|G蛋白偶联受体|神经科学
分子量 254.25
纯度 99.10%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Dyphylline|二羟丙茶碱|Diprophylline

溶解度

H2O:47 mg/mL (184.9 mM),DMSO:48 mg/mL (188.8 mM),Ethanol:<1 mg/mL

参考文献

1.Schwabe U, et al. Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):212-21.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2