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Dimethoxycurcumin

Dimethoxycurcumin (Veratrylcurcuminoid) 是 curcumin 衍生物，拥有抗氧化及抗炎作用。

CAS号

160096-59-3

分子式

C23H24O6

主要靶点

Others

仅限科研使用

Cat No : CM05152

Print datasheet

Synonyms

Veratrylcurcuminoid|二甲氧基姜黄素

验证数据展示

  • CAS No.: 160096-59-3

    Dimethoxycurcumin
    CAS#: 160096-59-3

产品信息

Dimethoxycurcumin is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes.

CAS号 160096-59-3
分子式 C23H24O6
主要靶点 Others
主要通路 其他
分子量 396.43
纯度 96.05%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 Veratrylcurcuminoid|二甲氧基姜黄素

溶解度

Ethanol:≤0.25mg/ml,dimethyl formamide:10mg/ml,DMSO:5mg/ml

参考文献

1.Zhao H, Liu Q et al. In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. Cancer Med. 2017 Jul;6(7):1698-1706.
2.Teymouri M, Barati N, Pirro M, Sahebkar A. Biological and pharmacological evaluation of dimethoxycurcumin: A metabolically stable curcumin analogue with a promising therapeutic potential. J Cell Physiol. 2018 Jan;233(1):124-140.
3.Chen D, Dai F, Chen Z et al. Dimethoxy Curcumin Induces Apoptosis by Suppressing Survivin and Inhibits Invasion by Enhancing E-Cadherin in Colon Cancer Cells. Med Sci Monit. 2016 Sep 11;22:3215-22.
4.Hassan HE, Keita JA, Narayan L, Brady SM, Frederick R, Carlson S, Glass KC, Natesan S, Buttolph T, Fandy TE. The combination of dimethoxycurcumin with DNA methylation inhibitor enhances gene re-expression of promoter-methylated genes and antagonizes their cytotoxic effect. Epigenetics. 2016 Sep 2:1-10. [Epub ahead of print] PubMed PMID: 27588609; PubMed Central PMCID: PMC5094623.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2