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DTHIB

CAS号

897326-30-6

分子式

C13H9ClFN3O3

主要靶点

HSP

仅限科研使用

Cat No : CM11442

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Synonyms

anticancer|cancer|inhibit|HSP90|HSP70|HSF1|HSP|HSP27|Heat shock proteins|degradation|DTHIB|nuclear|prostate|Inhibitor

验证数据展示

  • CAS No.: 897326-30-6

    DTHIB
    CAS#: 897326-30-6

产品信息

CAS号 897326-30-6
分子式 C13H9ClFN3O3
主要靶点 HSP
主要通路 代谢|细胞骨架
分子量 309.68
纯度 99.29%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
别名 anticancer|cancer|inhibit|HSP90|HSP70|HSF1|HSP|HSP27|Heat shock proteins|degradation|DTHIB|nuclear|prostate|Inhibitor

靶点活性

DTHIB binding to the HSF1 DNA binding domain:160 nM (Kd)

溶解度

DMSO:25 mg/mL (80.73 mM)

参考文献

1.Dong B , Jaeger A M , Hughes P F , et al. Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1[J]. Science Translational Medicine, 2020, 12(574):eabb5647.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2