验证数据展示
产品信息
83386-1-PBS targets DSC3 in Cytometric bead array, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | Cytometric bead array, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | DSC3 fusion protein Ag34648 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | desmocollin 3 |
| 别名 | CDHF3, desmocollin 3, Desmocollin 4, DSC, DSC1 |
| 计算分子量 | 100 kDa |
| GenBank蛋白编号 | NM_001941 |
| 基因名称 | DSC3 |
| Gene ID (NCBI) | 1825 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q14574 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Desmocollin-3 (DSC3), also known as CDHF3 and DSC4, is a member of the cadherin superfamily of calcium-dependent cell adhesion molecules and a major component of desmosomes. It has 2 isoforms with molecular masses of 100 and 93 kDa. It is particularly expressed in the vagina, testis, skin, oral mucosa and esophagus. Its subcellular localization is at the cell membrane. Post-translational modifications, including glycosylation, have been described.