DRC1 Polyclonal antibody

DRC1 Polyclonal Antibody for IF-P, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF-P, WB, ELISA

Conjugate

Unconjugated

Cat No : 26219-1-AP

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Synonyms

C2orf39, CCDC164, Coiled-coil domain-containing protein 164, DRC1, Dynein regulatory complex protein 1



经过测试的应用

Positive WB detected inmouse testis tissue, rat testis tissue
Positive IF detected inmouse testis tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26219-1-AP targets DRC1 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF-P, WB, ELISA
Tested Reactivity human, mouse, rat
Immunogen DRC1 fusion protein Ag24113 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chromosome 2 open reading frame 39
Synonyms C2orf39, CCDC164, Coiled-coil domain-containing protein 164, DRC1, Dynein regulatory complex protein 1
Observed Molecular Weight 87 kDa
GenBank Accession NumberBC009488
Gene Symbol C2orf39
Gene ID (NCBI) 92749
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96MC2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DRC1, also known as C2orf39, CCDC164, has 3 coiled-coil motifs in its N-terminal half and an additional coiled-coil motif near its C terminus. DRC1 is a subunit of the nexin-dynein regulatory complex, an axonemal structure critical for the regulation of ciliary dynein motors. DRC1 is predominantly expressed in the lung, brain, and prostate (PMID: 23354437). DRC1 deficiency disrupts the assembly of the nexin-dynein regulatory complex, causing ciliary dyskinesia(PMID: 23354437, 34815526).

实验方案

Product Specific Protocols
WB protocol for DRC1 antibody 26219-1-APDownload protocol
IF protocol for DRC1 antibody 26219-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols